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Antazoline (phosphate)

Product Specifications

UNSPSC Description

Antazoline phosphate is an H1 receptor antagonist that affects the activity of the central nervous system, has a potent antiarrhythmic effect[1][2][3].

Target Antigen

Histamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/antazoline-phosphate.html

Smiles

O=P(O)(O)O.C1(CN(C2=CC=CC=C2)CC3=CC=CC=C3)=NCCN1

Molecular Weight

363.35

References & Citations

[1]MariuszŚwiąder,et al. Influence of antazoline and ketotifen on the anticonvulsant activity of conventional antiepileptics against maximal electroshock in mice. Eur Neuropsychopharmacol. 2004 Aug;14(4):307-18.|[2]Jing Li, et al. Repurposing of Antazoline Hydrochloride as an Inhibitor of Hepatitis B Virus DNA Secretion. Virol Sin. 2021 Jun;36(3):501-509.|[3]Maciej T Wybraniec, et al. Efficacy and safety of antazoline for cardioversion of atrial fibrillation: propensity score matching analysis of a multicenter registry (CANT II Study). Pol Arch Intern Med. 2022 Jun 29;132(6):16234.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-B1067B/Antazoline-phosphate-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-B1067B/

Clinical Information

Launched

CAS Number

154-68-7

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