Recombinant Macaca fascicularis Membrane spanning 4-domains A1 (MS4A1) -VLPs (Active)
Product Specifications
Product Name Alternative
(Membrane spanning 4-domains A1) (Membrane-spanning 4-domains subfamily A member 1)
Abbreviation
Recombinant Cynomolgus monkey MS4A1 protein-VLPs (Active)
Gene Name
MS4A1
UniProt
M4ZHZ6
Expression Region
1-297aa
Organism
Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
Target Sequence
MTTPRNSVNGTFPAEPMKGPIAMQPGPKPLLRRMSSLVGPTQSFFMRESKALGAVQIMNGLFHIALGGLLMIPAGIYAPICVTVWYPLWGGIMYIISGSLLAATEKNSRKCLVKGKMIMNSLSLFAAISGMILSIMDILNIKISHFLKMESLNFIRVHTPYINIYNCEPANPSEKNSPSTQYCYSIQSLFLGILSVMLIFAFFQELVIAGIVENEWRRTCSRPKSSVVLLSAEEKKEQVIEIKEEVVGLTETSSQPKNEEDIEIIPIQEEEEEETETNFPEPPQDQESSPIENDSSP
Tag
C-terminal 10xHis-tagged (This tag can be tested only under denaturing conditions)
Type
MP-VLP Transmembrane Protein & Active Protein & In Stock Protein
Source
Mammalian cell
Field of Research
Cancer
Endotoxin
Less than 1.0 EU/μg as determined by LAL method.
Purity
The purity information is not available for VLPs proteins.
Activity
Yes
Bioactivity
Measured by its binding ability in a functional ELISA. Immobilized Macaca fascicularis CD20 at 10 μg/mL can bind Anti-CD20 recombinant antibody (CSB-RA015007MA3HU), the EC50 is 10.65-15.26 ng/mL. The VLPs (CSB-MP3838) is negative control.
Form
Lyophilized powder
Buffer
Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein indeionized sterile water to a concentration of 0.1-1.0 mg/mL.Aliquot for long-term storage at -80°C. Solubilize for 60 minutes at room temperature with occasional gentle mixing. Avoid vigorous shaking or vortexing.
Molecular Weight
34.4 kDa
References & Citations
"Novel humanized anti-CD20 antibody BM-ca binds to a unique epitope and exerts stronger cellular activity than others." Kobayashi H., Matsunaga Y., Uchiyama Y., Nagura K., Komatsu Y. Cancer Med. 2:130-143 (2013)
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Product MSDS
https://www.cusabio.com/msds/12934102/
Protein Length
Full Length
Available Sizes
Curated Selection
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