HPK1-IN-32
HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1].
Product Specifications
CAS Number
[2766481-17-6]
UNSPSC
12352005
Target
MAP4K
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hpk1-in-32.html
Concentration
10mM
Purity
98.72
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CC1=C(C(NCCN2CC[C@H](C2)F)=O)C(C)=CC(C3=NC(OC4=CN(C5CCN(CC5)C)N=C4)=C(N=C3)N)=C1
Molecular Formula
C28H37FN8O2
Molecular Weight
536.64
References & Citations
[1]Sanjia XU, et al. 3-[ (1h-pyrazol-4-yl) oxy]pyrazin-2-amine compounds as hpk1 inhibitor and use thereof. Patent. WO2022068848.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAP4K1/HPK1
Available Sizes
Curated Selection
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