Antibacterial agent 219

Antibacterial agent 219 (Compound 2/75c) exhibits antibacterial activity by targeting cell wall biosynthesis. Antibacterial agent 219 inhibits methicillin-resistant Staphylococcus aureus (MRSA) strains (MIC=0.5-32 µg/mL), Enterococcus faecium (MIC=2 µg/mL) and S. aureus (MIC=2 µg/mL) [1][2].

Product Specifications

CAS Number

[1649473-91-5]

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-219.html

Smiles

FC1=CC=C(C=C1)OC2=CC=C(C3=NOC(C4=CC5=C(NC=C5)C=C4)=N3)C=C2

Molecular Formula

C22H14FN3O2

Molecular Weight

371.36

References & Citations

[1]Ceballos S, et al., Activities of Oxadiazole Antibacterials against Staphylococcus aureus and Other Gram-Positive Bacteria. Antimicrob Agents Chemother. 2018 Jul 27;62 (8) :e00453-18.|[2]Chang M, et al., Non-beta lactam antibiotics. WO2016049586.