Antibacterial agent 219
Antibacterial agent 219 (Compound 2/75c) exhibits antibacterial activity by targeting cell wall biosynthesis. Antibacterial agent 219 inhibits methicillin-resistant Staphylococcus aureus (MRSA) strains (MIC=0.5-32 µg/mL), Enterococcus faecium (MIC=2 µg/mL) and S. aureus (MIC=2 µg/mL) [1][2].
Product Specifications
CAS Number
[1649473-91-5]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-219.html
Smiles
FC1=CC=C(C=C1)OC2=CC=C(C3=NOC(C4=CC5=C(NC=C5)C=C4)=N3)C=C2
Molecular Formula
C22H14FN3O2
Molecular Weight
371.36
References & Citations
[1]Ceballos S, et al., Activities of Oxadiazole Antibacterials against Staphylococcus aureus and Other Gram-Positive Bacteria. Antimicrob Agents Chemother. 2018 Jul 27;62 (8) :e00453-18.|[2]Chang M, et al., Non-beta lactam antibiotics. WO2016049586.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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