AN2718
AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.
Product Specifications
CAS Number
[174672-06-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/AN2718.html
Concentration
10mM
Purity
99.85
Solubility
DMSO : ≥ 250 mg/mL
Smiles
OB1OCC2=CC(Cl)=CC=C21
Molecular Formula
C7H6BClO2
Molecular Weight
168.39
Precautions
H302, H315, H319, H335
References & Citations
[1]Seiradake, et al. Antifungal activity and mechanism of action of a benzoxaborole, AN2718, which is in development for the treatment of tinea pedis. 48th Annual ICAAC/46th Annual IDSA (2008) .
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Curated Selection
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