AN2718

AN2718 inhibits fungal growth by blocking protein synthesis using the oxaborole tRNA trapping (OBORT) mechanism.

Product Specifications

CAS Number

[174672-06-1]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/AN2718.html

Concentration

10mM

Purity

99.85

Solubility

DMSO : ≥ 250 mg/mL

Smiles

OB1OCC2=CC(Cl)=CC=C21

Molecular Formula

C7H6BClO2

Molecular Weight

168.39

Precautions

H302, H315, H319, H335

References & Citations

[1]Seiradake, et al. Antifungal activity and mechanism of action of a benzoxaborole, AN2718, which is in development for the treatment of tinea pedis. 48th Annual ICAAC/46th Annual IDSA (2008) .

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 1

Available Sizes

Curated Selection

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