VEGFR2-IN-2
VEGFR2-IN-2 (compound 6e) is a potent and selective VEGFR2 inhibitor with an IC50 of 19.32 nM. VEGFR2-IN-2 can be used for researching
Product Specifications
CAS Number
[737818-56-3]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
VEGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vegfr2-in-2.html
Concentration
10mM
Purity
99.26
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
BrC1=CC=C(COC2=C3C=CC=CC3=NC=N2)C=C1
Molecular Formula
C15H11BrN2O
Molecular Weight
315.16
Precautions
H315, H319
References & Citations
[1]Sun J, et al. Design, synthesis, biological evaluation, and molecular modeling study of 4-alkoxyquinazoline derivatives as potential VEGFR2 kinase inhibitors. Org Biomol Chem. 2013 Nov 28;11 (44) :7676-86.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
VEGFR2/KDR/Flk-1
Available Sizes
Curated Selection
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