KP-6
KP-6, a polypeptide, is a Wnt/β-catenin signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD) [1].
Product Specifications
CAS Number
2102414-23-1
UNSPSC
12352209
Target
Wnt; β-catenin
Type
Peptides
Related Pathways
Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/kp-6.html
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(C)C)NC([C@H]([C@H](O)C)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H]2N(CCC2)C([C@@H](N)CCC(N)=O)=O)=O)=O)=O)=O)=O)C(N[C@@H](CC3=CN=CN3)C(N[C@H](C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N4[C@@H](CCC4)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CC(O)=O)C(N[C@H](C(O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O)=O)=O)CC6=CNC7=CC=CC=C67)=O)=O)=O)CC8=CC=C(C=C8)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC9=CNC%10=CC=CC=C9%10)=O)=O
Molecular Formula
C159H232N46O44
Molecular Weight
3491.83
References & Citations
[1]Youhua Liu, et al. Purposes of the micromolecule polypeptide KP 6 in the medicine for preparing treatment CKD. CN106822865A.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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