HTopo-II/tubulin-IN-1
HTopo-II/tubulin-IN-1 (compound 5L) is a hTopo-II/tubulin inhibitor. hTopo-II/tubulin-IN-1 inhibits cell migration and can be used in anti-cancer research[1].
Product Specifications
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/htopo-ii-tubulin-in-1.html
Smiles
O=C1N2C(C=CC=C2)=NC(C3=CN=C4C(C=CC=C4)=C3)=C1C5=CC=C(Cl)C=C5
Molecular Formula
C23H14ClN3O
Molecular Weight
383.83
References & Citations
[1]Saini M, et al. Scaffold overlay of flavonoid-inspired molecules: Discovery of 2,3-diaryl-pyridopyrimidin-4-imine/ones as dual hTopo-II and tubulin targeting anticancer agents. Bioorg Chem. 2024 Nov;152:107738.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC041003-500 1x 500 µL
Mucin 5AC (MUC5AC) (58M1), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC050391-100 1x 100 µL
CD81 / TAPA-1 (1.3.3.22), CF405M conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC881429-100 1x 100 µL
E-Cadherin / CD324 (Intercellular Junction Marker) (4A2), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680630-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC940788-100 1x 100 µL
MART-1 / Melan-A (MLANA/788), CF594 conjugate, 0.1mg/mL
Sign In for Pricing
View Details