[pThr3]-CDK5 Substrate

[pThr3]-CDK5 Substrate is an effective Phospho-Thr3CDK5 Substrate. [pThr3]-CDK5 Substrate is derived from the sequence of the histone H1 peptide that docks in the active site of CDK5. [pThr3]-CDK5 Substrate is phosphorylated by CDK5 with a Km value of 6 µM[1].

Product Specifications

CAS Number

[1670273-47-8]

UNSPSC

12352209

Target

CDK

Type

Peptides

Related Pathways

Cell Cycle/DNA Damage

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/pthr3-cdk5-substrate.html

Solubility

H2O

Smiles

O=C([C@@H]1CCCN1)N[C@@H](CCCCN)C(N[C@]([C@@H](C)OP(O)(O)=O)([H])C(N2[C@@H](CCC2)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(O)=O)CC(C)C)=O)=O)=O)=O)=O)=O)=O)=O

Molecular Formula

C53H100N15O15P

Molecular Weight

1218.43

References & Citations

[1]Beaudette KN, et al. Substrate specificity characterization of a cdc2-like protein kinase purified from bovine brain. J Biol Chem. 1993 Oct 5;268 (28) :20825-30.