Phosphodiesterase 10-IN-2
Phosphodiesterase 10-IN-2 (THPP-4) is an oral active phosphodiesterase 10A (PDE10A) inhibitor with the Ki of 4.5 nM. Phosphodiesterase 10-IN-2 can be used for study of schizophrenia[1].
Product Specifications
CAS Number
[1257051-56-1]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phosphodiesterase-10-in-2.html
Smiles
O=C(C1=CN(C=N1)C)N2CCC3=NC(C4=CC=C(N=C4)Cl)=NC(OC(C)C)=C3C2
Molecular Formula
C20H21ClN6O2
Molecular Weight
412.87
References & Citations
[1]Raheem IT, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2012 Sep 15;22 (18) :5903-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
More Discoveries
Explore Other Products
Browse additional items from our catalog
![5-Chlorobenzo[d]thiazole](https://cdn.genprice.uk/products/572/8096065746945/imageurl/trc-c429098-5g.webp)
![Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
MBS1320730-01 0.02 mg (E-Coli)
Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)
Sign In for Pricing
View Details MBS1320730-02 0.1 mg (E-Coli)
Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)
Sign In for Pricing
View Details ![Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
MBS1320730-03 0.02 mg (Yeast)
Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)
Sign In for Pricing
View Details ![Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)](https://cdn.genprice.uk/genprice/uk/genprice5.webp)
MBS1320730-04 0.02 mg (Baculovirus)
Recombinant Bacillus anthracis Bis (5'-nucleosyl) -tetraphosphatase prpE [asymmetrical] (prpE)
Sign In for Pricing
View Details