Phosphodiesterase 10-IN-2
Phosphodiesterase 10-IN-2 (THPP-4) is an oral active phosphodiesterase 10A (PDE10A) inhibitor with the Ki of 4.5 nM. Phosphodiesterase 10-IN-2 can be used for study of schizophrenia[1].
Product Specifications
CAS Number
[1257051-56-1]
UNSPSC
12352005
Target
Phosphodiesterase (PDE)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/phosphodiesterase-10-in-2.html
Smiles
O=C(C1=CN(C=N1)C)N2CCC3=NC(C4=CC=C(N=C4)Cl)=NC(OC(C)C)=C3C2
Molecular Formula
C20H21ClN6O2
Molecular Weight
412.87
References & Citations
[1]Raheem IT, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2012 Sep 15;22 (18) :5903-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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