Amlexanox (Standard)
Amlexanox (Standard) is the analytical standard of Amlexanox. This product is intended for research and analytical applications. Amlexanox (AA673; Amoxanox; CHX3673) is a specific inhibitor of IKKε and TBK1, and inhibits the IKKε and TBK1 activity determined by MBP phosphorylation with an IC50 of approximately 1-2 μM.
Product Specifications
CAS Number
68302-57-8
Product Name Alternative
AA673 (Standard) ; Amoxanox (Standard) ; CHX3673 (Standard)
UNSPSC
12352005
Target
IKK; Reference Standards
Type
Reference Standards
Related Pathways
NF-κB; Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/amlexanox-standard.html
Smiles
O=C(C1=C(N)N=C2C(C(C3=CC(C(C)C)=CC=C3O2)=O)=C1)O
Molecular Formula
C16H14N2O4
Molecular Weight
298.29
References & Citations
[1]Reilly SM, et al. An inhibitor of the protein kinases TBK1 and IKK-e improves obesity-related metabolic dysfunctions in mice. Nat Med. 2013 Mar;19 (3) :313-21.|[2]Bell, J. AmLexanox for the treatment of recurrent aphthous ulcers. Clin Drug Investig, 2005. 25 (9) : p. 555-66.|[3]Zhang Y, et al. AmLexanox Suppresses Osteoclastogenesis and Prevents Ovariectomy-Induced Bone Loss. Sci Rep. 2015 Sep 4;5:13575.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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