Olpadronic acid
Product Specifications
UNSPSC Description
Olpadronic acid (Olpadronate) is an orally active amino-bisphosphonate and inhibits bone resorption. Olpadronic acid also prevents bone destruction and tumor growth in the skeletal prostate cancer mouse model. Olpadronic acid can be used for research of osteoporosis, malignancies and rheumatoid arthritis[1][2].
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/olpadronic-acid.html
Purity
95.0
Solubility
H2O : 50 mg/mL (ultrasonic;warming)
Smiles
O=P(O)(C(CCN(C)C)(P(O)(O)=O)O)O
Molecular Weight
263.12
References & Citations
[1]Roldán EJ, et al. Olpadronate: a new amino-bisphosphonate for the treatment of medical osteopathies. Expert Opin Investig Drugs. 1998 Sep;7(9):1521-38. |[2]Yang M, et al. The bisphosphonate olpadronate inhibits skeletal prostate cancer progression in a green fluorescent protein nude mouse model. Clin Cancer Res. 2006 Apr 15;12(8):2602-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-106431/Olpadronic-acid-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-106431/Olpadronic-acid-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
63132-39-8
Curated Selection
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