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(Rac) -E1R

(Rac) -E1R (Compound 2) is the racemate of E1R. (Rac) -E1R is a sigma-1 receptor positive allosteric modulator (Sig1R PAM) used for the research of cognition/memory disorders[1].

Product Specifications

CAS Number

787623-60-3

UNSPSC

12352005

Target

Sigma Receptor

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/rac-e1r.html

Concentration

10mM

Purity

98.48

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N)CN1C(C)C(C2=CC=CC=C2)CC1=O

Molecular Formula

C13H16N2O2

Molecular Weight

232.28

References & Citations

[1]Veinberg G, et al. Synthesis and biological evaluation of 2- (5-methyl-4-phenyl-2-oxopyrrolidin-1-yl) -acetamide stereoisomers as novel positive allosteric modulators of sigma-1 receptor. Bioorg Med Chem. 2013 May 15;21 (10) :2764-71.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Sigma 1 Receptor

Available Sizes

Frequently Asked Questions

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