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M-Coumaric acid (Standard)

M-Coumaric acid (Standard) is the analytical standard of m-Coumaric acid. This product is intended for research and analytical applications. m-Coumaric acid is a polyphenol metabolite from caffeic acid, formed by the gut microflora and the amount in human biofluids is diet-dependant. m-Coumaric acid is a BBB-penetrant metabolite of chlorogenic acid. m-Coumaric acid stimulates the cerebral nerves in vitro. m-Coumaric acid can evoke neurite outgrowth in hippocampal neuronal cells. m-Coumaric acid can promote neuronal differentiation. m-Coumaric acid increases spontaneous locomotor activity in mice by acting on the central nervous system. m-Coumaric acid inhibits the oxidation of L-dopa by epidermis tyrosinase. m-Coumaric acid attenuates non-catalytic protein glycosylation in retinas of diabetic rats[1][2][3].

Product Specifications

CAS Number

588-30-7

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

Endogenous Metabolite; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/m-coumaric-acid-standard.html

Purity

99.91

Smiles

O=C(O)/C=C/C1=CC=CC(O)=C1

Molecular Formula

C9H8O3

Molecular Weight

164.16

Precautions

H315, H319, H335

References & Citations

[1]Ito H, et al. Chlorogenic acid and its metabolite m-coumaric acid evoke neurite outgrowth in hippocampal neuronal cells. Biosci Biotechnol Biochem. 2008 Mar;72 (3) :885-8.|[2]Cabanes, J., et al., (1984) . Kinetic study on the slow inhibition of epidermis tyrosinase by m-coumaric acid. Biochimica et biophysica acta, 790 (2), 101–107.|[3]Moselhy Said Salama, et al., m-Coumaric acid attenuates non-catalytic protein glycosylation in the retinas of diabetic rats. Journal of Pesticide Science. Online ISSN : 1349-0923. ISSN-L : 0385-1559.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed and dry storage, away from light and moisture

Scientific Category

Reference Standards

Available Sizes

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