2OH-BNPP1
2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.
Product Specifications
CAS Number
[833481-73-5]
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2OH-BNPP1.html
Purity
99.65
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC1=CC=CC=C1CC2=NN(C(C)(C)C)C3=NC=NC(N)=C32
Molecular Formula
C16H19N5O
Molecular Weight
297.35
References & Citations
[1]Nyati S, et al. The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Sci Signal. 2015 Jan 6;8 (358) :ra1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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