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2OH-BNPP1

2OH-BNPP1 is an inhibitor of BUB1 kinase, a Ser/Thr kinase, used for the treatment of cancer.

Product Specifications

CAS Number

833481-73-5

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/2OH-BNPP1.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=CC=C1CC2=NN(C(C)(C)C)C3=NC=NC(N)=C32

Molecular Formula

C16H19N5O

Molecular Weight

297.35

References & Citations

[1]Nyati S, et al. The kinase activity of the Ser/Thr kinase BUB1 promotes TGF-β signaling. Sci Signal. 2015 Jan 6;8 (358) :ra1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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