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5′-O-[ (4-Cyanophenyl) methyl]-2′,3′-O- (1-methylethylidene) adenosine

5′-O-[ (4-Cyanophenyl) methyl]-2′,3′-O- (1-methylethylidene) adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].

Product Specifications

CAS Number

[1134156-51-6]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/5-o-4-cyanophenyl-methyl-2-3-o-1-methylethylidene-adenosine.html

Solubility

10 mM in DMSO

Smiles

NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H](COCC4=CC=C(C#N)C=C4)[C@@H]5[C@H]3OC(C)(C)O5

Molecular Formula

C21H22N6O4

Molecular Weight

422.44

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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