Profenofos

Profenofos is an insecticida used on field crops, vegetables, and fruit crops. Profenofos is an acetylcholinesterase (AChE) inhibitor, with neurotoxicity[1].

Product Specifications

CAS Number

[41198-08-7]

UNSPSC

12352005

Hazard Statement

H302, H312, H317, H332, H400, H410

Target

Cholinesterase (ChE) ; Insecticide

Type

Reference compound

Related Pathways

Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/profenofos.html

Purity

96.07

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=P(OCC)(SCCC)OC1=CC=C(Br)C=C1Cl

Molecular Formula

C11H15BrClO3PS

Molecular Weight

373.63

Precautions

H302, H312, H317, H332, H400, H410

References & Citations

[1]Madhulika Kushwaha, et al. Kushwaha, M., et al.. Profenofos, an Acetylcholinesterase-Inhibiting Organophosphorus Pesticide: A Short Review of Its Usage, Toxicity, and Biodegradation. J Environ Qual.2016 Sep;45 (5) :1478-1489.|[2]Prabhavathy Das G, et al. Cytotoxicity and genotoxicity induced by the pesticide profenofos on cultured human peripheral blood lymphocytes. Drug Chem Toxicol. 2006;29 (3) :313-22.|[3]El-Bendary H M, et al. Histopathological changes associated with exposure of male mice to profenofos and chlorpyrifos[J]. Annual Research & Review in Biology, 2014, 4 (5) : 766.