Ac-IETD-AMC
Ac-IETD-AMC is a fluorogenic caspase-8/granzyme B substrate containing the acetyl (Ac) moiety. Ac-IETD-AMC is frequently used to measure caspase-8 activity[1].
Product Specifications
CAS Number
348079-17-4
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-ietd-amc.html
Solubility
10 mM in DMSO
Smiles
CC(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O)=O)=O)=O)=CC1=O
Molecular Formula
C31H41N5O12
Molecular Weight
675.68
References & Citations
[1]V Frost, et al. Exploitation of a non-apoptotic caspase to regulate the abundance of the cdkI p27 (KIP1) in transformed lymphoid cells. Oncogene. 2001 May 17;20 (22) :2737-48.
Shipping Conditions
Room temperature
Scientific Category
Dye Reagents
Clinical Information
No Development Reported
Frequently Asked Questions
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