Sulanemadlin
Sulanemadlin (ALRN-6924) is a potent and cell-permeating p53-based peptidomimetic macrocycles. Sulanemadlin is a inhibitor of the p53-MDM2, p53-MDMX, or both p53 and MDM2 and MDMX protein-protein interactions. Sulanemadlin can be used for cancers research[1].
Product Specifications
CAS Number
1451199-98-6
Product Name Alternative
ALRN-6924; MP-4897
UNSPSC
12352209
Target
MDM-2/p53
Type
Peptides
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sulanemadlin.html
Purity
96.17
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C([C@@H](NC([C@@H](NC([C@@](C)(CCCCCC/C=C/CCC[C@](C)(NC([C@@H](NC([C@@H](NC([C@@H](NC1=O)C)=O)CCC(N)=O)=O)CC(C)C)=O)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](C)C(N[C@H](C)C(N)=O)=O)=O)=O)=O)=O)=O)NC([C@@H](NC([C@H]([C@H](O)C)NC([C@@H](NC(C)=O)CC(C)C)=O)=O)CC2=CC=CC=C2)=O)=O)CCC(O)=O)=O)CC3=CC=C(C=C3)O)N[C@H]1CC4=CNC5=CC=CC=C45
Molecular Formula
C95H140N20O23
Molecular Weight
1930.25
References & Citations
[1]Manuel AIVADO, et al. Peptidomimetic macrocycles and uses thereof. WO2018208954A2
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light, under nitrogen)
Scientific Category
Peptides
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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