JNJ-28583867
JNJ-28583867 is an orally active and selective histamine H3 receptor antagonist (Ki=10.6 nM) and serotonin transporter (SERT) inhibitor (Ki=3.7 nM) . JNJ-28583867 can be used in the research of depression[1].
Product Specifications
CAS Number
892407-39-5
UNSPSC
12352005
Target
Histamine Receptor; Serotonin Transporter
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/jnj-28583867.html
Smiles
CSC1=CC=C([C@@H]2CN(C)CC3=C2C=CC(OCCCN4CCOCC4)=C3)C=C1
Molecular Formula
C24H32N2O2S
Molecular Weight
412.59
References & Citations
[1]Barbier A J, et al. Pharmacological characterization of JNJ-28583867, a histamine H3 receptor antagonist and serotonin reuptake inhibitor[J]. European journal of pharmacology, 2007, 576 (1-3) : 43-54.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H3 Receptor
Frequently Asked Questions
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