Disodium terephthalate

Disodium terephthalate (Terephthalic acid disodium salt) is an isomer and a precursor of polyester PET, which can be used to make clothing and plastics. Disodium terephthalate can be used to build skin tumor models[1].

Product Specifications

CAS Number

[10028-70-3]

Product Name Alternative

Terephthalic acid (disodium salt)

UNSPSC

12352200

Hazard Statement

H301+H311+H331

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/disodium-terephthalate.html

Purity

99.93

Solubility

H2O : 70 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C(O[Na])=O)C=C1)O[Na]

Molecular Formula

C8H4Na2O4

Molecular Weight

210.09

Precautions

H301+H311+H331

References & Citations

[1]Heck HD, et al. The induction of bladder stones by terephthalic acid, dimethyl terephthalate, and melamine (2,4,6-triamino-s-triazine) and its relevance to risk assessment. Regul Toxicol Pharmacol. 1985 Sep;5 (3) :294-313. |[2]Saito M, et al. CENP-50 is required for papilloma development in the two-stage skin carcinogenesis model. Cancer Sci. 2020 Aug;111 (8) :2850-2860. |[3]Cui L, et al. Deregulation of the p16-cyclin D1/cyclin-dependent kinase 4-retinoblastoma pathway involved in the rat bladder carcinogenesis induced by terephthalic acid-calculi. Urol Res. 2006 Oct;34 (5) :321-8. |[4]Ball GL, et al. Toxicological review and oral risk assessment of terephthalic acid (TPA) and its esters: A category approach. Crit Rev Toxicol. 2012 Jan;42 (1) :28-67.