Sulbactam pivoxil

Sulbactam pivoxil (Pivsulbactam) is a prodrug of Sulbactam (HY-B0334) with oral activity. Sulbactam is a β-lactamase inhibitor with antibacterial activity. Sulbactam pivoxil is better absorbed than Sulbactam and results in higher serum levels after oral administration[1][2].

Product Specifications

CAS Number

[69388-79-0]

Product Name Alternative

Pivsulbactam; CP 47904

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Antibiotic; Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/sulbactam-pivoxil.html

Purity

98.0

Solubility

DMSO : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C([C@@H](C(C)(C)S([C@]1([H])C2)(=O)=O)N1C2=O)OCOC(C(C)(C)C)=O

Molecular Formula

C14H21NO7S

Molecular Weight

347.38

Precautions

H302, H315, H319, H335

References & Citations

[1]Changov LS, et al. An efficient method for the synthesis of sulbactam pivoxil. Farmaco. 2000;55 (2) :134-135. |[2]English A R, et al. Orally effective acid prodrugs of the. beta.-lactamase inhibitor sulbactam. Journal of medicinal chemistry, 1990, 33 (1) : 344-347.