Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LASSBio-2052

LASSBio-2052 is a derivative of N-acylhydrazone with antitumor activity against hepatocellular carcinoma (HCC) . LASSBio-2052 inhibits HCC cells HepG2 and Hep3B, with IC50 of 18 and 41 μM. LASSBio-2052 arrests the cell cycle at G2/M phase, through downregulation of FOXM1. LASSBio-2052 induces apoptosis in HCC cells[1].

Product Specifications

CAS Number

2549160-15-6

UNSPSC

12352005

Target

Apoptosis; DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Apoptosis; Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/lassbio-2052.html

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=CC=C(C(F)(F)F)C=C1)C2=CC=CC=C2NCC3=CC=C(OC)C(O)=C3

Molecular Formula

C23H20F3N3O3

Molecular Weight

443.42

References & Citations

[1]Andrade AAR, et al., Antiproliferative Activity of N-Acylhydrazone Derivative on Hepatocellular Carcinoma Cells Involves Transcriptional Regulation of Genes Required for G2/M Transition. Biomedicines. 2024 Apr 18;12 (4) :892.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Avacopan
TRC-A245770-25MG 25 mg

Avacopan

Sign In for Pricing
View Details
Bisphenol P
TRC-B519475-5G 5 g

Bisphenol P

Sign In for Pricing
View Details
DOCK8 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI8D9]
TA801833BM 100 µL

DOCK8 Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI8D9]

Sign In for Pricing
View Details
Strept. Avidin Peroxidase Colloidal Gold, 1mL 5nm
HGA-02-5 1 mL

Strept. Avidin Peroxidase Colloidal Gold, 1mL 5nm

Sign In for Pricing
View Details
Frozen Tissue Sections, Neurovascular bundle
CS626725 5x 5 µm

Frozen Tissue Sections, Neurovascular bundle

Sign In for Pricing
View Details
MRP8/14 (S100A8/A9) Mouse Monoclonal Antibody [Clone ID: FP 64]
AM31907PU-N 100 µg

MRP8/14 (S100A8/A9) Mouse Monoclonal Antibody [Clone ID: FP 64]

Sign In for Pricing
View Details