Z-Gly-Gly-Phe-OH
Z-Gly-Gly-Phe-OH is a substrate for pepsin and thermolysin. Z-Gly-Gly-Phe-OH has an IC50 of 15.8 μM for open sodium channels under pepsin catalysis. Z-Gly-Gly-Phe-OH forms peptide bonds with amine components (such as H-Leu-NHPh) through enzyme-catalyzed condensation reactions, and is active as an intermediate in peptide synthesis[1][2].
Product Specifications
CAS Number
[13171-93-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Endogenous Metabolite; Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/z-gly-gly-phe-oh.html
Purity
99.46
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NC(CNC(CNC(OCC2=CC=CC=C2)=O)=O)=O
Molecular Formula
C21H23N3O6
Molecular Weight
413.42
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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