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EKLF (Acetyl Lys274) rabbit pAb

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype. [provided by RefSeq, Oct 2009],

Product Specifications

Background

This gene encodes a hematopoietic-specific transcription factor that induces high-level expression of adult beta-globin and other erythroid genes. The zinc-finger protein binds to the DNA sequence CCACACCCT found in the beta hemoglobin promoter. Heterozygous loss-of-function mutations in this gene result in the dominant In (Lu) blood phenotype. [provided by RefSeq, Oct 2009]

UniProt

Q13351

Swiss Prot

Q13351

Reactivity

Human; Rat; Mouse

Immunogen

Synthesized peptide derived from human EKLF (Acetyl Lys274)

Clonality

Polyclonal

Source

Rabbit

Applications

WB; ELISA

Concentration

1 mg/ml

Dilution

WB 1:1000-2000 ELISA 1:5000-20000

Molecular Weight

40kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

40kD

Fragment

IgG

Subcellular Location

Nucleus . Colocalizes with SUMO1 in nuclear speckles. .

Other Product Names

Krueppel-like factor 1 (Erythroid krueppel-like transcription factor; EKLF)

Gene ID (Human)

10661

Available Sizes

Curated Selection

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