Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

LY 344864

LY 344864 is a selective, orally active 5-HT1F receptor agonist with a Ki of 6 nM. LY 344864 is a full agonist producing an effect similar in magnitude to serotonin itself. LY 344864 can cross the blood brain barrier to some extent[1].

Product Specifications

CAS Number

186544-26-3

UNSPSC

12352005

Hazard Statement

H317, H319

Target

5-HT Receptor; Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ly-344864.html

Concentration

10mM

Purity

98.59

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC2=C(NC3=C2C[C@H](N(C)C)CC3)C=C1)C4=CC=C(F)C=C4

Molecular Formula

C21H22FN3O

Molecular Weight

351.42

Precautions

H317, H319

References & Citations

[1]Phebus LA, Johnson KW, Zgombick JM, Characterization of LY344864 as a pharmacological tool to study 5-HT1F receptors: binding affinities, brainpenetration and activity in the neurogenic dural inflammation model of migraine. Life Sci. 1997;61 (21) :2117-26.|[2]Scholpa NE, et al. 5-HT1F receptor-mediated mitochondrial biogenesis for the treatment of Parkinson's disease. Br J Pharmacol. 2018 Jan;175 (2) :348-358.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

5-HT1 Receptor; lactoferrin; mLAG-3; MUC3; α adrenergic receptor; α-1 microglobulin

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

IRAK Recombinant Antibody, Cy3 Conjugated
bsm-61058R-Cy3-01 20 µL

IRAK Recombinant Antibody, Cy3 Conjugated

Sign In for Pricing
View Details
IRAK Recombinant Antibody, Cy3 Conjugated
bsm-61058R-Cy3-02 100 µL

IRAK Recombinant Antibody, Cy3 Conjugated

Sign In for Pricing
View Details
PRKG1 (Protein Kinase, cGMP Dependent Type I) BioAssayTM ELISA Kit (Human) discontinued
384151 96 Tests

PRKG1 (Protein Kinase, cGMP Dependent Type I) BioAssayTM ELISA Kit (Human) discontinued

Sign In for Pricing
View Details
DMTr-2'-O-C22-rU-3'-CE-Phosphoramidite
PA065-10 10 g

DMTr-2'-O-C22-rU-3'-CE-Phosphoramidite

Sign In for Pricing
View Details
Rabbit Polyclonal LENG1 Antibody [Alexa Fluor 750]
NBP2-41357AF750 0.1 mL

Rabbit Polyclonal LENG1 Antibody [Alexa Fluor 750]

Sign In for Pricing
View Details
FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (fkpA) Antibody (HRP)
abx345857-01 50 µL

FKBP-type peptidyl-prolyl cis-trans isomerase FkpA (fkpA) Antibody (HRP)

Sign In for Pricing
View Details