HSP90/LSD1-IN-1
HSP90/LSD1-IN-1 (compound 6) is a HSP90/LSD1 dual inhibitor. HSP90/LSD1-IN-1 inhibits the proliferation of prostate cancer cell lines PC-3 and DU145, with GI50 values of 0.24 and 0.30 μM, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Histone Demethylase; HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hsp90-lsd1-in-1.html
Smiles
O=C(N(CC)C1=CC=CC(CN(C)CC#C)=C1)C2=CC(C(C)C)=C(O)C=C2O
Molecular Formula
C23H28N2O3
Molecular Weight
380.48
References & Citations
[1]Tang DW, et al. HSP90/LSD1 dual inhibitors against prostate cancer as well as patient-derived colorectal organoids. Eur J Med Chem. 2024 Nov 15;278:116801.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HSP90; KDM1/LSD1
Frequently Asked Questions
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