(5R) -Dinoprost (tromethamine)

(5R) -Dinoprost tromethamine (Prostaglandin F2β tromethamine) is a metabolite produced by the metabolism of arachidonic acid cyclooxygenase. (5R) -Dinoprost tromethamine induces dose-dependent release of hexosaccharide containing mucin[1][2].

Product Specifications

CAS Number

[89847-02-9]

Product Name Alternative

Prostaglandin F2β (tromethamine) ; PGF2β (tromethamine)

UNSPSC

12352211

Hazard Statement

H302-H360

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5r-dinoprost-tromethamine.html

Solubility

10 mM in DMSO

Smiles

CCCCC[C@@H](/C=C/[C@@H]1[C@@H](C/C=C\CCCC(O)=O)[C@@H](C[C@H]1O)O)O.OCC(N)(CO)CO

Molecular Formula

C24H45NO8

Molecular Weight

475.62

Precautions

P264-P270-P280-P330-P405-P501

References & Citations

[1]Lamont JT, et, al. Cysteamine and prostaglandin F2 beta stimulate rat gastric mucin release. Gastroenterology. 1983 Feb;84 (2) :306-13.|[2]Jang Y, et, al. Molecular mechanisms underlying the actions of arachidonic acid-derived prostaglandins on peripheral nociception. J Neuroinflammation. 2020 Jan 22;17 (1) :30.