Human BDH2 Protein

<strong>Human BDH2 Protein</strong>_x000D_ <strong>Catalog number:</strong> B2011639_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 100 µg_x000D_ <strong>Molecular Weight or Concentration:</strong> 1 mg/mL_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20 °C_x000D_ <strong>Keywords:</strong> 3-hydroxybutyrate dehydrogenase type 2 protein, UCPA-OR protein, BDH-2 protein, SDR15C1 protein, PRO20933 protein, BDH-2, BDH 2, BDH2, FLJ13261 protein, DHRS6 protein, BDH 2 protein, UNQ6308, EFA6R protein_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Liu JZ, Hu YL, Feng Y, Jiang Y, Guo YB, Liu YF, Chen X, Yang JL, Chen YY, Mao QS, Xue WJ. BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer J Exp Clin Cancer Res. 2020 Jun 30;39(1):123._x000D_ 2: Yang WC, Lin SF, Wang SC, Tsai WC, Wu CC, Wu SC. The Effects of Human BDH2 on the Cell Cycle, Differentiation, and Apoptosis and Associations with Leukemia Transformation in Myelodysplastic Syndrome Int J Mol Sci. 2020 Apr 25;21(9):3033._x000D_ 3: Yang WC, Tsai WC, Lin PM, Yang MY, Liu YC, Chang CS, Yu WH, Lin SF. Human BDH2, an anti-apoptosis factor, is a novel poor prognostic factor for de novo cytogenetically normal acute myeloid leukemia J Biomed Sci. 2013 Aug 14;20(1):58._x000D_ 4: Li B, Liao Z, Mo Y, Zhao W, Zhou X, Xiao X, Cui W, Feng G, Zhong S, Liang Y, Du C, Huang G, Li P, Xiao X, Zhou X, Wang R, Zhang Z. Inactivation of 3-hydroxybutyrate dehydrogenase type 2 promotes proliferation and metastasis of nasopharyngeal carcinoma by iron retention Br J Cancer. 2020 Jan;122(1):102-110._x000D_ 5: Liu Z, Ciocea A, Devireddy L. Endogenous siderophore 2,5-dihydroxybenzoic acid deficiency promotes anemia and splenic iron overload in mice Mol Cell Biol. 2014 Jul;34(13):2533-46._x000D_ 6: Zughaier SM, Stauffer BB, McCarty NA. Inflammation and ER stress downregulate BDH2 expression and dysregulate intracellular iron in macrophages J Immunol Res. 2014;2014:140728._x000D_ 7: Zhao M, Li MY, Gao XF, Jia SJ, Gao KQ, Zhou Y, Zhang HH, Huang Y, Wang J, Wu HJ, Lu QJ. Downregulation of BDH2 modulates iron homeostasis and promotes DNA demethylation in CD4(+) T cells of systemic lupus erythematosus Clin Immunol. 2018 Feb;187:113-121._x000D_ 8: Liu Z, Lanford R, Mueller S, Gerhard GS, Luscieti S, Sanchez M, Devireddy L. Siderophore-mediated iron trafficking in humans is regulated by iron J Mol Med (Berl). 2012 Oct;90(10):1209-21._x000D_ 9: Liu Z, Li Y, Liu Y, Yang D, Jiao Y, Liu Y. Expression and clinical significance of BDH1 in liver cancer Medicine (Baltimore). 2021 Dec 3;100(48):e28013._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/35150746">10: Kwiatkowski S, Bozko M, Zarod M, Witecka A, Kocdemir K, Jagielski AK, Drozak J. Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104) J Biol Chem. 2022 Mar;298(3):101708. </a>_x000D_ _x000D_ <strong>Products Related to Human BDH2 Protein can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>