Stephanine

Stephanine ((-) -Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer[1][2].

Product Specifications

CAS Number

[517-63-5]

Product Name Alternative

(-) -Stephanine; l-Stephanine

UNSPSC

12352005

Target

Apoptosis; Parasite

Type

Natural Products

Related Pathways

Anti-infection; Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/stephanine.html

Solubility

10 mM in DMSO

Smiles

CN1CCC(C2=C3C4=CC=CC(OC)=C4C[C@@]12[H])=CC5=C3OCO5

Molecular Formula

C19H19NO3

Molecular Weight

309.36

References & Citations

[1]Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583.|[2]Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31 (9) :1357-1368.