Stephanine
Stephanine ((-) -Stephanine) is an isoquinoline aporphine-type alkaloid. Stephanine induce apoptosis through the reverse of mitotic exit. Stephanine exhibits Antiplasmodial activity. Stephanine can be used for the research of stomach pain, abdominal pain, arthritis and cancer[1][2].
Product Specifications
CAS Number
517-63-5
Product Name Alternative
(-) -Stephanine; l-Stephanine
UNSPSC
12352005
Target
Apoptosis; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/stephanine.html
Solubility
10 mM in DMSO
Smiles
CN1CCC(C2=C3C4=CC=CC(OC)=C4C[C@@]12[H])=CC5=C3OCO5
Molecular Formula
C19H19NO3
Molecular Weight
309.36
References & Citations
[1]Cui L, et, al. The anti-inflammatory and analgesic activities of 2Br-Crebanine and Stephanine from Stephania yunnanenses H. S.Lo. Front Pharmacol. 2023 Jan 4;13:1092583.|[2]Le PM, et, al. Stephanine from Stephania venosa (Blume) Spreng Showed Effective Antiplasmodial and Anticancer Activities, the Latter by Inducing Apoptosis through the Reverse of Mitotic Exit. Phytother Res. 2017 Sep;31 (9) :1357-1368.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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