Manzamine A (hydrochloride)

[1]Hamann M, et al. Glycogen synthase kinase-3 (GSK-3) inhibitory activity and structure-activity relationship (SAR) studies of the manzamine alkaloids. Potential for Alzheimer's disease. J Nat Prod. 2007;70 (9) :1397-1405.|[2]Winkler JD, et al. Antimalarial activity of a new family of analogues of manzamine A. Org Lett. 2006;8 (12) :2591-2594.|[3]Kallifatidis G, et al. The marine natural product manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells [published correction appears in Mar Drugs. 2014;12 (4) :2305-7]. Mar Drugs. 2013;11 (9) :3500-3516. Published 2013 Sep 17.|[4]Palem JR, et al. Manzamine A as a novel inhibitor of herpes simplex virus type-1 replication in cultured corneal cells. Planta Med. 2011;77 (1) :46-51.|[5]Wahba AE, et al. Structure-activity relationship studies of manzamine A: amidation of positions 6 and 8 of the beta-carboline moiety. Bioorg Med Chem. 2009 Nov 15;17 (22) :7775-82. |[6]Donia M, et al. Marine natural products and their potential applications as anti-infective agents. Lancet Infect Dis. 2003 Jun;3 (6) :338-48. |[7]El Sayed KA, et al. New manzamine alkaloids with potent activity against infectious diseases. J Am Chem Soc. 2001 Mar 7;123 (9) :1804-8.