Astodrimer

Product Specifications

CAS Number

[1379746-42-5]

UNSPSC Description

Astodrimer (SPL7013 free base) is a large (3-4 nm,?~?16.5 kDa), negatively charged, highly-branched dendrimer, is a potent virucidal agent. Astodrimer shows antiviral and virucidal activity against a broad spectrum of viruses, including SARS-CoV-2, HIV-1, HSV-1, HSV-2, HPV. Astodrimer also has antibacterial properties[1][2][3].

Target Antigen

Bacterial; HCV; SARS-CoV

Type

Peptides

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/astodrimer.html

Solubility

10 mM in DMSO

Smiles

[Astodrimer]

References & Citations

[1]Paull JRA, et al. Virucidal and antiviral activity of astodrimer sodium against SARS-CoV-2 in vitro. Antiviral Res. 2021 Jul;191:105089.|[2]Romanowski EG, et al. Topical Astodrimer Sodium, a Non-Toxic Polyanionic Dendrimer, Demonstrates Antiviral Activity in an Experimental Ocular Adenovirus Infection Model. Molecules. 2021 Jun 5;26(11):3419.