[Ac-Tyr1, D-Phe2]GRF 1-29, amide (human)
[Ac-Tyr1, D-Phe2]GRF 1-29, amide (human), a growth hormone releasing factor (GRF) analogue, is a vasoactive intestinal peptide (VIP) antagonist[1].
Product Specifications
CAS Number
[93965-89-0]
UNSPSC
12352209
Target
GCGR
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ac-tyr1-d-phe2-grf-1-29-amide-human.html
Solubility
H2O
Smiles
OC(C=C1)=CC=C1C[C@H](NC(C)=O)C(N[C@H](CC2=CC=CC=C2)C(N[C@@H](CC(O)=O)C(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCSC)C(N[C@@H](CO)C(N[C@H](C(N)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)CC4=CC=CC=C4)=O)=O)=O)=O)=O
Molecular Formula
C157H252N44O43S
Molecular Weight
3476.01
References & Citations
[1]Waelbroeck M, et al. Interaction of growth hormone-releasing factor (GRF) and 14 GRF analogs with vasoactive intestinal peptide (VIP) receptors of rat pancreas. Discovery of (N-Ac-Tyr1, D-Phe2) -GRF (1-29) -NH2 as a VIP antagonist. Endocrinology. 1985 Jun;116 (6) :2643-9.|[2]Dufes C, et al. Effects of the vasoactive intestinal peptide (VIP) and related peptides on glioblastoma cell growth in vitro. J Mol Neurosci. 2003;21 (2) :91-102.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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