HDAC-IN-72
HDAC-IN-72 (compound 7j) is the most potent HDAC1 (IC50=0.65 μM), HDAC2 (IC50=0.78 μM), HDAC3 (IC50=1.70 μM) inhibitor and antiproliferative compound. HDAC-IN-72 can be used for breast cancer research[1].
Product Specifications
CAS Number
[763066-77-9]
UNSPSC
12352005
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hdac-in-72.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C(C(NC2=CC=CC=C2N)=O)C=C1)C3=CC=C(C)C=C3
Molecular Formula
C22H21N3O2
Molecular Weight
359.42
References & Citations
[1]Cheshmazar N, et al. Key structural requirements of benzamide derivatives for histone deacetylase inhibition: design, synthesis and biological evaluation[J]. Future Medicinal Chemistry, 2024 (0) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC2; HDAC3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![ADPRH, CT (ADPRH, ARH1, [Protein ADP-ribosylarginine] hydrolase, ADP-ribose-L-arginine cleaving enzyme) (APC)](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
MBS6271872-01 0.2 mL
ADPRH, CT (ADPRH, ARH1, [Protein ADP-ribosylarginine] hydrolase, ADP-ribose-L-arginine cleaving enzyme) (APC)
Ask
View Details MBS6271872-02 5x 0.2 mL
ADPRH, CT (ADPRH, ARH1, [Protein ADP-ribosylarginine] hydrolase, ADP-ribose-L-arginine cleaving enzyme) (APC)
Ask
View Details 
044422-ML550 100 µL
ZSWIM2, CT (ZSWIM2, ZZZ2, E3 ubiquitin-protein ligase ZSWIM2, MEKK1-related protein X, ZZ-type zinc finger-containing protein 2, Zinc finger SWIM domain-containing protein 2) (MaxLight 550) discontinued
Ask
View Details 132958-PE 100 µL
SAMD4A (Sterile alpha Motif Domain-containing Protein 4A, SAM domain-containing Protein 4A, SAMD4, KIAA1053, Protein Smaug Homolog 1, Smaug 1, SMAUG1, hSmaug1, SMAUG, SMG, SMGA) (PE)
Ask
View Details 