GCPII-IN-1

GCPII-IN-1 (Compound 2) is a GCPII (also known as PSMA) inhibitor scaffold with a Ki of 44.3 nM. GCPII-IN-1 can be used in the research of prostate cancer[1].

Product Specifications

CAS Number

[1025796-32-0]

UNSPSC

12352211

Target

Carboxypeptidase; PSMA

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/gcpii-in-1.html

Purity

99.83

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O

Molecular Formula

C12H21N3O7

Molecular Weight

319.31

References & Citations

[1]Jan Tykvart, et al. Rational design of urea-based glutamate carboxypeptidase II (GCPII) inhibitors as versatile tools for specific drug targeting and delivery. Bioorg Med Chem. 2014 Aug 1;22 (15) :4099-108.