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Human EREG Protein, Fc Tag

EREG is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4), which stimulates tyrosine phosphorylation of EGFR and ERBB4. EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, EREG may promote the progression of cancers of various human tissue.

Product Specifications

Background

EREG is a ligand of the epidermal growth factor receptor (EGFR) and the structurally related erb-b2 receptor tyrosine kinase 4 (ERBB4), which stimulates tyrosine phosphorylation of EGFR and ERBB4. EREG may be involved in a wide range of biological processes including inflammation, wound healing, oocyte maturation, and cell proliferation. Additionally, EREG may promote the progression of cancers of various human tissue.

Specifications

This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 31.7 kDa. The protein migrates as 33-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

O14944-1

Expression Region

Val 63 - Leu 108

Host

HEK293

Target

EREG

Conjugation

Unconjugated

Tag

N-Fc

Source

Human

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Molecular Weight

31.7 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

500ug*2

Host or Source

HEK293

Species

Human

Protein ID

O14944-1

Preservative

Trehalose

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