Tau Peptide (275-305) (Repeat 2 domain)
Product Specifications
UNSPSC Description
Tau Peptide (275-305) (Repeat 2 domain) is the Alzheimer's tau fragment R2, corresponding to the second repeat unit of the microtubule-binding domain, which is believed to be pivotal to the biochemical properties of full tau protein[1].
Target Antigen
Tau Protein
Type
Peptides
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/tau-peptide-275-305-repeat-2-domain.html
Purity
98.83
Solubility
DMSO : 12.5 mg/mL (adjust pH to 3 with 1 M HCL)
Smiles
CC(C)[C@H](N)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CS)C(NCC(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCCCN)C(N[C@@H](CC1=CN=CN1)C(N[C@@H](C(C)C)C(N2[C@@H](CCC2)C(NCC(NCC(NCC(N[C@@H](CO)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
3264.71
References & Citations
[1]Dan-Jing Yang, et al. Mercury(II) promotes the in vitro aggregation of tau fragment corresponding to the second repeat of microtubule-binding domain: Coordination and conformational transition. Biopolymers. 2010 Dec;93(12):1100-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2516/Tau-Peptide-275-305-Repeat-2-domain-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2516/Tau-Peptide-275-305-Repeat-2-domain-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
330456-25-2
Available Sizes
Curated Selection
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