Sideroxylin
Sideroxylin is a C-methylated flavone isolated from Callistemon lanceolatus and exerts antimicrobial activity against Staphylococcus aureus. Sideroxylin inhibits ovarian cancer cell proliferation and induces apoptosis, causing DNA fragmentation, depolarization of the mitochondrial membrane, the generation of reactive oxygen species (ROS) [1].
Product Specifications
CAS Number
3122-87-0
UNSPSC
12352005
Target
Apoptosis; Bacterial; Reactive Oxygen Species (ROS)
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/sideroxylin.html
Purity
97.00
Solubility
DMSO : 15.5 mg/mL (ultrasonic; warming)
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=C(C)C(OC)=C(C)C(O)=C13
Molecular Formula
C18H16O5
Molecular Weight
312.32
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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