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UG-480

UG-480 is a gemini analog that effectively stabilizes the active VDR conformation. UG-480 has antiproliferative effects in estrogen receptor-positive MCF-7 breast adenocarcinoma cells. UG-480 can be used in cancer research[1].

Product Specifications

UNSPSC

12352211

Target

VD/VDR

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ug-480.html

Smiles

CC(CCC[C@@H]([C@@H]1C[C@H]1CCC(C)(C)O)[C@@]2([H])CC[C@]3(/C(CCC[C@]23C)=C/C=C4C[C@H](C[C@@H](C/4=C)O)O)[H])(C)O

Molecular Formula

C34H56O4

Molecular Weight

528.81

References & Citations

[1]Gómez-Bouzó, et al. "Design, Synthesis, and Biological Evaluation of New Type of Gemini Analogues with a Cyclopropane Moiety in Their Side Chain." Journal of Medicinal Chemistry (2024) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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