C-Kit-IN-1
C-Kit-IN-1 is a potent inhibitor of c-Kit and c-Met with IC50s of <200 nM.
Product Specifications
CAS Number
[1225278-16-9]
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
C-Kit; c-Met/HGFR
Type
Reference compound
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/c-Kit-IN-1.html
Purity
98.83
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1(CC1)C(NC2=CC=CC=C2)=O)NC3=CC(F)=C(OC4=CC=NC(C5=CN(C)N=C5)=C4)C=C3F
Molecular Formula
C26H21F2N5O3
Molecular Weight
489.47
Precautions
H315, H319, H335
References & Citations
[1]Daniel L. Flynn, et al. Cyclopropane amides and analogs exhibiting anti-cancer and anti-proliferative activities. WO 2010051373 A1
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Curated Selection
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