EXP3179
Product Specifications
Product Name Alternative
Tyrphostin NT157
UNSPSC Description
EXP3179 is an important intermediate aldehyde metabolite of Losartan. EXP3179 has no AT1-R–blocking activity, but potently inhibits the expression of endothelial cyclooxygenase (COX)-2. EXP3179 exerts potent anti-inflammatory actions[1].
Target Antigen
COX
Type
Reference compound
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/exp3179.html
Purity
98.08
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
[H]N1N=NN=C1C2=CC=CC=C2C3=CC=C(C=C3)CN4C(C([H])=O)=C(N=C4CCCC)Cl
Molecular Weight
420.89
References & Citations
[1]Rossi GP. Losartan metabolite EXP3179: an AT1-receptor-independent treatment strategy for patients with the metabolic syndrome?. Hypertension. 2009;54(4):710-712.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-114950/EXP3179-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-114950/EXP3179-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
114798-36-6
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
