Ebelactone A Microbial

<strong>Ebelactone A Microbial</strong>_x000D_ <strong>Catalog number:</strong> B2014233_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> 338.48 g/mol_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −20°C_x000D_ <strong>Keywords:</strong> Ebelactone A microbial_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ostrowska H, Kalinowska J, Chabielska E, Stankiewicz A, Kruszewski K, Buczko W. Ebelactone B, an inhibitor of extracellular cathepsin A-type enzyme, suppresses platelet aggregation ex vivo in renovascular hypertensive rats J Cardiovasc Pharmacol. 2005 Apr;45(4):348-53._x000D_ 2: Wyatt MA, Ahilan Y, Argyropoulos P, Boddy CN, Magarvey NA, Harrison PH. Biosynthesis of ebelactone A: isotopic tracer, advanced precursor and genetic studies reveal a thioesterase-independent cyclization to give a polyketide _-lactone J Antibiot (Tokyo). 2013 Jul;66(7):421-30._x000D_ 3: Umezawa H, Aoyagi T, Uotani K, Hamada M, Takeuchi T, Takahashi S. Ebelactone, an inhibitor of esterase, produced by actinomycetes J Antibiot (Tokyo). 1980 Dec;33(12):1594-6._x000D_ 4: Ostrowska H, Dabrowska M, Osada J, Mantur M. Effects of ebelactone B on cathepsin A activity in intact platelets and on platelet activation Rocz Akad Med Bialymst. 2003;48:150-3._x000D_ 5: Uotani K, Naganawa H, Aoyagi T, Umezawa H. Biosynthetic studies of ebelactone A and B by 13C NMR spectrometry J Antibiot (Tokyo). 1982 Dec;35(12):1670-4._x000D_ 6: Nonaka Y, Ohtaki H, Ohtsuka E, Kocha T, Fukuda T, Takeuchi T, Aoyagi T. Effects of ebelactone B, a lipase inhibitor, on intestinal fat absorption in the rat J Enzyme Inhib. 1996;10(1):57-63._x000D_ 7: Uotani K, Naganawa H, Kondo S, Aoyagi T, Umezawa H. Structural studies on ebelactone A and B, esterase inhibitors produced by actinomycetes J Antibiot (Tokyo). 1982 Nov;35(11):1495-9._x000D_ 8: Majima M, Ikeda Y, Kuribayashi Y, Mizogami S, Katori M, Aoyagi T. Ebelactone B, an inhibitor of urinary carboxypeptidase Y-like kininase, prevents the development of deoxycorticosterone acetate-salt hypertension in rats Eur J Pharmacol. 1995 Sep 15;284(1-2):1-11._x000D_ 9: Ito H, Majima M, Nakajima S, Hayashi I, Katori M, Izumi T. Effect of prolonged administration of a urinary kinase inhibitor, ebelactone B on the development of deoxycorticosterone acetate-salt hypertension in rats Br J Pharmacol. 1999 Feb;126(3):613-20._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8089934">10: Majima M, Kuribayashi Y, Ikeda Y, Adachi K, Kato H, Katori M, Aoyagi T. Diuretic and natriuretic effect of ebelactone B in anesthetized rats by inhibition of a urinary carboxypeptidase Y-like kininase Jpn J Pharmacol. 1994 May;65(1):79-82. </a>_x000D_ _x000D_ <strong>Products Related to Ebelactone A Microbial can be found at</strong> <a href="https://moleculardepot.com/product-category/Chemicals/"> Chemicals</a>