Ellipyrone B
Ellipyrone B, an antihyperglycemic γ-pyrone enclosed macrocyclic polyketide, shows inhibition potential against dipeptidyl peptidase-4 (IC50=0.48 mM) [1].
Product Specifications
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ellipyrone-b.html
Solubility
10 mM in DMSO
Smiles
CCOC1C/C=C/C2CC(C=C(C(C(CC(CC(OC(C1)C)=O)O)=O)CCC(C)C)O2)=O
Molecular Formula
C25H38O7
Molecular Weight
450.57
References & Citations
[1]Paulose, S.K., et al. Ellipyrones A-B, from oval bone cuttlefish Sepia elliptica: Antihyperglycemic γ-pyrone enclosed macrocyclic polyketides attenuate dipeptidyl peptidase-4 and carbolytic enzymes. Med Chem Res 31, 462–473 (2022) .
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
DPP-4
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