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Dapagliflozin (Standard)

Dapagliflozin (Standard) is the analytical standard of Dapagliflozin. This product is intended for research and analytical applications. Dapagliflozin (BMS-512148), a new type of agent used to treat diabetes mellitus (DM), is a competitive sodium/glucose cotransporter 2 (SGLT2) inhibitor, which results in excretion of glucose into the urine[1]. Dapagliflozin induces HIF1 expression and attenuates renal IR injury[2].

Product Specifications

CAS Number

[461432-26-8]

Product Name Alternative

BMS-512148 (Standard)

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Reference Standards; SGLT

Type

Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Others

Field of Research

Metabolic Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/dapagliflozin-standard.html

Purity

99.96

Smiles

O[C@H]1[C@H](C2=CC(CC3=CC=C(OCC)C=C3)=C(Cl)C=C2)O[C@H](CO)[C@@H](O)[C@@H]1O

Molecular Formula

C21H25ClO6

Molecular Weight

408.87

Precautions

H302, H315, H319, H335

References & Citations

[1]Pelissier T, et al. The orofacial capsaicin test in rats: effects of different capsaicin concentrations and morphine. Pain. 2002 Mar;96 (1-2) :81-7.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed and dry storage, away from light and moisture

Scientific Category

Reference Standards

Isoform

SGLT2

Available Sizes

Curated Selection

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