Pterinotoxin-1
Pterinotoxin-1 is a sodium channel inhibitor peptide toxin[1].
Product Specifications
UNSPSC
12352209
Target
Sodium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pterinotoxin-1.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CC(O)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H]1CCCCN)=O)=O)=O)=O)NC2=O)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CCSC)C(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]4CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O)=O)NC1=O)C(N[C@@H](CC(O)=O)C(N7[C@@H](CCC7)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]2CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CC8=CC=C(C=C8)O)C(N[C@@H](C(C)C)C(N[C@@H](CC(C)C)C(N)=O)=O)=O)=O)=O)NC4=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Molecular Formula
C163H251N49O53S7
Molecular Weight
3969.49
References & Citations
[1]Zhang Y Y, et al. Structural and functional diversity of peptide toxins from tarantula Haplopelma hainanum (Ornithoctonus hainana) venom revealed by transcriptomic, peptidomic, and patch clamp approaches[J]. Journal of Biological Chemistry, 2015, 290 (22) : 14192-14207.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Nav1.3; Nav1.7; Nav1.8
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