(S) -HexylHIBO
(S) -HexylHIBO is the S-enantiomer of HexylHIBO. HexylHIBO is a group I mGluR antagonist. HexylHIBO elevates the hypothalamus-pituitary-adrenal axis response to restraint in rats. HexylHIBO is promising for research of central nervous system-related diseases[1][2].
Product Specifications
CAS Number
334887-48-8
UNSPSC
12352005
Target
MGluR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/s-hexylhibo.html
Smiles
O=C(O)[C@@H](N)CC(ON1)=C(CCCCCC)C1=O
Molecular Formula
C12H20N2O4
Molecular Weight
256.30
References & Citations
[1]Evanson NK, et al. Metabotropic glutamate receptor-mediated signaling dampens the HPA axis response to restraint stress. Physiol Behav. 2015 Oct 15;150:2-7.|[2]Madsen U, et al. 4-Alkylated homoibotenic acid (HIBO) analogues: versatile pharmacological agents with diverse selectivity profiles towards metabotropic and ionotropic glutamate receptor subtypes. Neuropharmacology. 2005;49 Suppl 1:114-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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