Ibuterol (hydrochloride)

Ibuterol (KWD 2058) hydrochloride, a diester of Terbutaline (HY-B0802A), is an orally active, selective and effective β-stimulating agent with lipophilic activities. Ibuterol hydrochloride is also an orally active ocular hypotensive agent. Ibuterol hydrochloride relieves bronchial obstruction in asthma without causing circulatory effects. Ibuterol hydrochloride is proming for rasearch of intraocular hypertension, asthma and bronchitis[1][2][3].

Product Specifications

CAS Number

[57576-17-7]

Product Name Alternative

KWD 2058 (hydrochloride)

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ibuterol-hydrochloride.html

Smiles

O=C(C(C)C)OC1=CC(C(CNC(C)(C)C)O)=CC(OC(C(C)C)=O)=C1.Cl

Molecular Formula

C20H32ClNO5

Molecular Weight

401.92

References & Citations

[1]Arner B, et al. Comparison between ibuterol hydrochloride and terbutaline in asthma. Br Med J. 1976 Jan 10;1 (6001) :72-4.|[2]Phipps TL, et al. Effects of ibuterol, a beta-2 adrenergic prodrug, on intraocular pressure. J Ocul Pharmacol. 1986 Summer;2 (3) :225-37. |[3]Larsson S, et al. Comparison of intravenous ibuterol (KWD 2058), a new bronchodilator, and terbutaline. Eur J Clin Pharmacol. 1977 Jul 19;11 (6) :429-33.