IA2, Human (His)

The IA2 protein is critical in the vesicle-mediated secretion process and is essential for the accumulation of secretory vesicles in the hippocampus, pituitary gland, and pancreatic islets. IA2 is critical for insulin-related functions, ensuring normal levels of insulin-containing vesicles, preventing degradation and promoting glucose-stimulated insulin secretion. IA2 Protein, Human (His) is the recombinant human-derived IA2 protein, expressed by E. coli , with N-6*His labeled tag.

RQQDKERLAA LGPEGAHGDT TFEYQDLCRQ HMATKSLFNR AEGPPEPSRV SSVSSQFSDA AQASPSSHSS TPSWCEEPAQ ANMDISTGHM ILAYMEDHLR NRDRLAKEWQ ALCAYQAEPN TCATAQGEGN IKKNRHPDFL PYDHARIKLK VESSPSRSDY INASPIIEHD PRMPAYIATQ GPLSHTIADF WQMVWESGCT VIVMLTPLVE DGVKQCDRYW PDEGASLYHV YEVNLVSEHI WCEDFLVRSF YLKNVQTQET RTLTQFHFLS WPAEGTPAST RPLLDFRRKV NKCYRGRSCP IIVHCSDGAG RTGTYILIDM VLNRMAKGVK EIDIAATLEH VRDQRPGLVR SKDQFEFALT AVAEEVNAIL KALPQ