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CAIX/CAXII-IN-2

CAIX/CAXII-IN-2 (compound 23) is a CAIX/CAXII inhibitor, with Ki values ​​of 8.9 nM and 5.3 nM for CAIX/CAXII, respectively. CAIX/CAXII-IN-2 can be used in cancer research[1].

Product Specifications

UNSPSC

12352005

Target

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/caix-caxii-in-2.html

Smiles

O=S(C1=CC=C(C2=NC(N)=NC(C3=CC=CC=C3)=C2)C=C1)(N)=O

Molecular Formula

C16H14N4O2S

Molecular Weight

326.37

References & Citations

[1]Aslan H, et al. Benzenesulfonamide decorated dihydropyrimidin (thi) ones: carbonic anhydrase profiling and antiproliferative activity. RSC Med Chem. 2024 Mar 26;15 (6) :1929-1941.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

CA IX; CA XII

Curated Selection

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